What’s the Difference Between DMHA vs DMAA?


DMHA (Octodrine) is a psychoactive stimulant of the central nervous system. DMHA vs DMAA which was initially studied as a nasal decongestant but has recently begun to appear in a variety of pre-workouts, formulations for fat burning.

DMHA is naturally occurring. though most products available include a synthetic version. that’s identical or very similar to the naturally occurring DMHA/Octodrine.

DMHA’s molecular structure is remarkably similar to DMAA, which is why DMHA is frequently considered the twin brother of DMAA. DMHA is a potent stimulant, also referred to as Octodrine, Dimethylhexylamine or 2-Aminoisoheptane. It’s used in two forms when talking about 2-aminoisoheptane:

  • 2-Amino-5-Methylheptane
  • 2-Amino-6-Methylheptane

The 2-Amino-6-Methylheptane form is typically utilized in pre-workout goods and’fat burner’ products. The most study was done on this sort of DMHA, and supplement companies most frequently use it as it is less costly to produce.

How DMHA (Octodrine) Works

DMHA functions like other psychoactive amines on our central nervous system, insofar as its stimulating function.

DMHA’s most crucial activity mechanism is increasing catecholamine release and activating the brain’s reward centre. Reward pathway activation on your nervous system contributes to elevated amounts of dopamine, norepinephrine, and dopamine. These effects are shown to create cognitive, mood, and performance-enhancing properties of Octodrine.

Increased energy is the advantage of DMHA affinity to the reception of TAAR1 following DMHA. This institution, by activating adenylyl cyclase, increases the production of cAMP.

DMHA is reported to be an extremely favourable stimulant, with fewer reported side effects than DMAA.

Benefits of DMHA

DMHA is reported to be a highly favourable stimulant, with fewer reported side effects than DMAA.

  • I have increased energy levels.
  • Improved mood.
  • I have increased mental focus.
  • Decreased appetite.
  • Bronchial dilation.
  • Fat burning properties.
  • Decreased fatigue.

In various fat burners or pre-workout items, you may often find DMHA. As it’s quite special, it’s become one of the essential stimulants for pre-workout formulations.

DMHA has been demonstrated to provide very similar effects to DMAA, albeit without the same risk of unwanted effects. Some people also say Octodrine is more powerful, but this will probably be variable between individuals.

The impacts of DMHA are often contrasted with those two banned substances – Ephedrine and AMP Citrate. Anecdotal experiences notice the many advantages of Octodrine for physical endurance, strength, performance improvement, and cognitive/mood enhancement. Some people today seem to use DMHA as a research aid.


DMAA is significantly more potent on a milligram basis. ~50mg of DMAA is supposed to work similarly to 150-200 mg of DMHA. At precisely the exact same time, it is more challenging to acquire high-quality DMAA-containing supplements, and DMAA is prohibited in dietary supplements.  

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